Isabelle Villemure
GRSTB Regular MemberÉcole Polytechnique
Assistant Professor
Mechanical and Biomedical Engineering
Coordinates:
| Phone Number: | 514-340-4711 ext.: 4900 |
| Fax: | 514-340-4176 |
| Email: | isabelle.villemure@polymtl.ca |
| Website: | http://www.polymtl.ca/recherche/rc/professeurs/details.php?NoProf=292 |
| Office: | A-111.2 |
| Civic Address: | Campus de l'Université de Montréal 2900, boul. Édouard Montpetit École Polytechnique 2500, chemin de Polytechnique |
| Postal Address: | C.P. 6079, succ. Centre-Ville Montréal, Québec H3C 3A7 Montréal (Québec, H3T 1J4) Canada |
| Additional Coordinates | |
| Institution: | CHU Sainte-Justine |
| Office: | #4715 |
| Phone Number: | 514-345-4931 x6076 |
| Fax: | 514-345-4801 |
Research:
| Title: | Mechanobilogy of the cartilaginous growth plates |
| Description: | The fundamental objective of my research is to improve our understanding of the mechanical regulation of growth and development of bone tissues, both in normal developmental conditions as well as in pathological progressive deformities of the musculo-skeletal system. The research aims at determining the basic mechanisms governing the cellular response of growing bone tissue to its mechanical environment, by investigating and overlaping three complementary avenues of research: I) Experimental tissue and cell mechanics (to characterize stress-strain relationships of growth plates, their cells and certain cellular components in response to loading); II) Mechanotransduction (to establish in vivo the metabolic responses of growing bones to loading); and III) Biomechanical modeling (to develop computer models to investigate the mechanical growth modulation and pathological progressive deformities. In the long term, it is anticipated that these research projects will provide a scientific basis for the orthopedic treatment of musculo-skeletal progressive deformities. Key words: biomechanical modeling, , , mechanical growth modulation, growth plate. |
| Axes of Biomedical Applications: | Musculoskeletal |
| Technological Approaches: | Biomechanics, Nanotechnology and microsystems |
| Expertise: | growth plate, mechanical growth modulation, mechanobiology, biomechanical modeling, experimental tissue and cell mechanics |