|
Recent Publications |
 |
| |
Jean M, Alameh M, De Jesus D, Thibault M, Lavertu M, Darras V, Nelea M, Buschmann MD, Merzouki A. (2012). "Chitosan-based therapeutic nanoparticles for combination gene therapy and gene silencing of in vitro cell lines relevant to type 2 diabetes" European Journal of Pharmaceutical Science 45(1-2): 138-149. PDF
| Bizet A. A., Tran-Khanh N., Saksena A., Liu K., Buschmann M. D. and Philip A. (2012). "CD109-mediated degradation of TGF-β receptors and inhibition of TGF-β responses involve regulation of SMAD7 and Smurf2 localization and function" J. Cell Biochemistry 113(1): 238-246. PDF
| Gao C., Seuntjens J., Kaufman G. N., Tran-Khanh N., Butler A., Li A., Wang H., Buschmann M. D., Harvey E. J. and Henderson J. E. (2012). "Mesenchymal stem cell transplantation to promote bone healing" Journal of Orthopaedic Research Epub 6 JAN 2012 1-7. PDF
| Alameh M., DeJesus D., Jean M., Darras V., Thibault M., Lavertu M., Buschmann M. D. and Merzouki A (2012). "Low molecular weight chitosan nanoparticulate system at low N:P ratio for nontoxic polynucleotide delivery" International Journal of Nanomedecine In press 1-16. PDF
| Guzman-Morales J., Ariganello M. B., Hammami I., Thibault M., Jolicoeur M. and Hoemann C. D. (2011). "Biodegradable chitosan particles induce chemokine release and negligible arginase-1 activity compared to IL-4 in murine bone marrow-derived macrophages" Biochemical and Biophysical Research Communications 405(4): 538-544. PDF
| Hoemann C., Kandel R., Roberts S., Saris D. B. F., Creemers L. B., Mainil-Varlet P., Methot S., Hollander A. P. and Buschman M. D. (2011). "International Cartilage Repair Society (ICRS) Recommended Guidelines for Histological Endpoints for Cartilage Repair Studies in Animal Models and Clinical Trials " Cartilage 2(2): 153-172. PDF
| Jean M., Alameh M., Buschmann M. D. and Merzouki A. (2011). "Effective and safe gene-based delivery of GLP-1 using chitosan/plasmid-DNA therapeutic nanocomplexes in an animal model of type 2 diabetes" Gene Therapy 18(8): 807-816. PDF
| Changoor A., Tran-Khanh N., Methot S., Garon M., Hurtig M. B., Shive M. S. and Buschmann M. D. (2011). "A polarized light microscopy method for accurate and reliable grading of collagen organization in cartilage repair" Osteoarthritis and Cartilage 19(1): 126-135. PDF
| Thibault M., Astolfi M., Tran-Khanh N., Lavertu M., Darras V., Merzouki A. and Buschmann M. D. (2011). "Excess polycation mediates efficient chitosan-based gene transfer by promoting lysosomal release of the polyplexes" Biomaterials 32(Epub ahead of print): 4639-4646. PDF
| Chen G., Sun J., Lascau-Coman V., Chevrier A., Marchand C. and Hoemann C. D. (2011). "Acute osteoclast activity following subchondral drilling is promoted by chitosan and associated with improved cartilage repair tissue integration" Cartilage 2(2): 173-185. PDF
| Changoor A., Coutu J. P., Garon M., Quenneville E., Hurtig M. B. and Buschman M. D. (2011). "Streaming potential-based arthroscopic device is sensitive to cartilage changes immediately post-impact in an equine cartilage injury model" Journal of Biomechanical Engineering-Transactions of the Asme 133(6): 1-10. PDF
| Changoor A., Nelea M., Méthot S., Tran-Khanh N., Chevrier A., Restrepo A., Shive M. S., Hoemann C. D. and Buschmann M. D. (2011). "Structural characteristics of the collagen network in human normal, degraded and repair articular cartilages observed in polarized light and scanning electron microscopies" Osteoarthritis Cartilage 19(12): 1458-1468. PDF
| Chen H. M., Chevrier A., Hoemann C. D., Sun J., Ouyang W. and Buschmann M. D. (2011). "Characterization of Subchondral Bone Repair for Marrow-Stimulated Chondral Defects and Its Relationship to Articular Cartilage Resurfacing" American Journal of Sports Medicine 39(8): 1731-1740. PDF
| Chen H., Hoemann C. D., Sun J., Chevrier A., McKee M. D., Shive M. S., Hurtig M. and Buschmann M. D. (2011). "Depth of subchondral perforation influences the outcome of bone marrow stimulation cartilage repair" Journal of Orthopaedic Research On-line(24-FEB-2011): 1-14. PDF
| Hurtig M., Buschman M. D., Fortier L. A., Hoemann C. D., Hunziker E., Jurvelin J., Mainil-Varlet P., McIlwraith C. W., Sah R. L. and Whiteside R. (2011). "Preclinical studies for cartilage repair: recommendations from the Internatinoal Cartilage Repair Society" Cartilage 2(2): 137-152. PDF
| Kazemi M., Li L. P., Savard P. and Buschmann M. D. (2011). "Creep behavior of the intact and meniscectomy knee joints" Journal of the Mechanical Behavior of Biomedical Materials 4(7): 1351-1358. PDF
| Lavertu M., Darras V. and Buschman M. D. (2011). "Kinetics and efficiency of chitosan reacetylation" Carbohydrate Polymers 87(2): 1192-1198. PDF
| Marchand C., Chen G., Tran-Khanh N., Sun J., Chen H., Buschmann M. D. and Hoemann C. D. (2011). "Microdrilled Cartilage Defects Treated with Thrombin-Solidified Chitosan/Blood Implant Regenerate a More Hyaline, Stable, and Structurally Integrated Osteochondral Unit Compared to Drilled Controls" Tissue Engineering Part A Epub 11 NOV 2011 1-12. PDF
| Kazemi M., Li L. P., Buschman M. D. and Savard P. (2011). "Partial meniscetomy changes fluid pressurization in articular cartilage in human knees" Journal of Biomechanical Engineering In press . PDF
| Marchand C., Chen H., Buschmann M. D. and Hoemann C. D. (2011). "Standardized 3D volumes of interest with adapted surfaces for more precise subchondral bone analyses by micro-CT" Tissue Engineering Part C-Methods 17(4): 475-484. PDF
| Bizet A. A., Liu K., Tran-Khanh N., Saksena A., Vorstenbosch J., Finnson K. W., Buschmann M. D. and Philip A. (2011). "The TGF-β co-receptor, CD109, promotes internalization and degradation of TGF-β receptors" Biochim Biophys Acta 1813(5): 742-753. PDF
| Chevrier A., Hoemann C. D., Sun J. and Buschmann M. D. (2010). "Temporal and spatial modulation of chondrogenic foci in subchondral microdrill holes by chitosan-glycerol phosphate/blood implant" Osteoarthritis and cartilage Epub ahead of print(xxx): 1-9. PDF
| Thibault M. M., S. Nimesh, M. Lavertu and MD. Buschmann (2010). " Intracellular trafficking and decondensation kinetics of Chitosan-pDNA polyplexes" Molecular therapy : the journal of the American Society of Gene Therapy 18(10): 1785-1795. PDF
| Nimesh S., Thibault M. M., Lavertu M. and Buschmann M. D. (2010). " Enhanced gene delivery mediated by low molecular weight chitosan/DNA complexes: effect of pH and serum" Molecular Biotechnology 46(2): 182-196. PDF
| Changoor A., Fereydoonzad L., Yaroshinsky A. and Buschmann M. D. (2010). " Effects of refrigeration and freezing on the electromechanical and biomechanical properties of articular cartilage" Journal of Biomechanical Engineering-Transactions of the Asme 132(6): 1-6. PDF
| Poole R., Blake S., Buschmann M., Goldring S., Laverty S., Lockwood S., Matyas J., McDougall J., Pritzker K., Rudolphi K., van den Berg W. and Yaksh T. (2010). "Recommendations for the use of preclinical models in the study and treatment of osteoarthritis" Osteoarthritis and Cartilage 18 S10-S16. PDF
| Tran-Khanh N., Chevrier A., Lascau-Coman V., Hoemann C. D. and Buschmann M. D. (2010). " Young Adult Chondrocytes Proliferate Rapidly and Produce a Cartilaginous Tissue at the Gel-Media Interface in Agarose Cultures" Connective Tissue Research 51(3): 216-223. PDF
| Finnson K. W., Parker W. L., Chi Y., Hoemann C. D., Goldring M. B., Antoniou J. and Philip A. (2010). "Endoglin differentially regulates TGF-beta-induced Smad2/3 and Smad1/5 signalling and its expression correlates with extracellular matrix production and cellular differentiation state in human chondrocytes" Osteoarthritis and Cartilage 18(11): 1518-1527. PDF
| Ma P. L., Buschmann M. D. and Winnik F. M. (2010). "One-Step Analysis of DNA/Chitosan Complexes by Field-Flow Fractionation Reveals Particle Size and Free Chitosan Content" Biomacromolecules 11(3): 549-554. PDF
| Hoemann C. D., Chen G. P., Marchand C., Tran-Khanh N., Thibault M., Chevrier A., Sun J., Shive M. S., Fernandes M. J. G., Poubelle P. E., Centola M. and El-Gabalawy H. (2010). " Scaffold-guided subchondral bone repair: Implication of neutrophils and alternatively activated Arginase-1+Macrophages" American Journal of Sports Medicine 38(9): 1845-1856. PDF
| Boucher C., Ruiz J. C., Thibault M., Buschmann M. D., Wertheimer M. R., Jolicoeur M., Durocher Y. and De Crescenzo G. (2010). " Human corneal epithelial cell response to epidermal growth factor tethered via coiled-coil interactions" Biomaterials 31(27): 7021-7031. PDF
| Marchand C., Bachand J., Perinet J., Baraghis E., Lamarre M., Rivard G. E., De Crescenzo G. and Hoemann C. D. (2010). " C3, C5, and factor B bind to chitosan without complement activation" Journal of Biomedical Materials Research Part A 93A(4): 1429-1441. PDF
| El-Bikai R., Welman M., Margaron Y., Cote J. F., Macqueen L., Buschmann M. D., Fahmi H., Shi Q., Maghni K., Fernandes J. C. and Benderdour M. (2010). " Perturbation of adhesion molecule-mediated chondrocyte-matrix interactions by 4-hydroxynonenal binding: implication in osteoarthritis pathogenesis" Arthritis Research & Therapy 12(5): 1-14. PDF
| MacQueen L. A., Buschmann M. D. and Wertheimer M. R. (2010). " Mechanical properties of mammalian cells in suspension measured by electro-deformation" Journal of Micromechanics and Microengineering 20(6): 1-11. PDF
| Alameh M., Jean M., DeJesus D., Buschmann M. D. and Merzouki A. (2010). "Chitosanase-based method for RNA isolation from cells transfected with chitosan/siRNA nanocomplexes for real-time RT-PCR in gene silencing" International Journal of Nanomedicine 5 473-481. PDF
| Darras V., Nelea M., Winnik F. M. and Buschmann M. D. (2010). " Chitosan modified with gadolinium diethylenetriaminepentaacetic acid for magnetic resonance imaging of DNA/chitosan nanoparticles" Carbohydrate Polymers 80(4): 1137-1146. PDF
| Ma P. L., Buschmann M. D. and Winnik F. M. (2010). " Complete physicochemical characterization of DNA/Chitosan complexes by multiple detection using asymmetrical Flow Field-Flow Fractionation" Analytical Chemistry 82(23): 9636-9643. PDF
| Ma P. L., Lavertu M., Winnik F. M. and Buschmann M. D. (2009). " New insights into chitosan-DNA interactions using isothermal titration microcalorimetry" Biomacromolecules 10(6): 1490-1499. PDF
| Jean M., Smaoui F., Lavertu M., Methot S., Bouhdoud L., Buschmann M. D. and Merzouki A. (2009). " Chitosan-plasmid nanoparticle formulations for IM and SC delivery of recombinant FGF-2 and PDGF-BB or generation of antibodies" Gene Therapy 16(9): 1097-1110. PDF
| Gigout A., Levasseur S., Girard-Lauriault P. L., Buschmann M. D., Wertheimer M. R. and Jolicoeur M. (2009). " CHO cells adhering to nitrogen-rich plasma-polymerised ethylene exhibit high production of a specific recombinant protein" Macromolecular Bioscience 9(10): 979-988. PDF
| Chen H., Sun J., Hoemann C.D, Lascau-Coman V., Ouyang W., McKee M. D., Shive M.S. and Buschmann M.D. (2009). " Drilling and microfracture lead to different bone structure and necrosis during bone-marrow stimulation for cartilage repair" Journal of Orthopaedic Research 27(11): 1432-1438. PDF
| Simard P., Galarneau H., Marois S., Rusu D., Hoemann C. D., Poubelle P. E., El-Gabalawy H. and Fernandes M. J. G. (2009). " Neutrophils exhibit distinct phenotypes toward chitosans with different degrees of deacetylation: implications for cartilage repair" Arthritis Research & Therapy 11(3): 1-10. PDF
| Hoemann C. D., El-Gabalawy H. and McKee M. D. (2009). " In vitro osteogenesis assays: Influence of the primary cell source on alkaline phosphatase activity and mineralization" Pathologie Biologie 57(4): 318-323. PDF
| Guzman-Morales J., El-Gabalawy H., Pham M. H., Tran-Khanh N., McKee M. D., Wu W., Centola M. and Hoemann C. D. (2009). " Effect of chitosan particles and dexamethasone on human bone marrow stromal cell osteogenesis and angiogenic factor secretion" Bone 45(4): 617-626. PDF
| Chevrier A., Nelea M., Hurtig M. B., Hoemann C. D. and Buschmann M. D. (2009). " Meniscus structure in human, sheep, and rabbit for animal models of meniscus repair" Journal of Orthopaedic Research 27(9): 1197-1203. PDF
|
|
| |
